Cystitis infection by E.coli

Abstract

A urinary tract infection (UTIs) are one of the most common pathological conditions in both community and hospital settings. Among the common uropathogens cause that associated to UTIs, UroPathogenic Escherichia coli (UPEC) is the primary cause it is one of the most common bacterial infections, UPEC strains possess large number of both structural (as fimbriae, pili , curli, flagella) and secreted (toxins, iron-acquisition systems) virulence factors that contribute to their capacity to cause disease, although the ability to adhere to the host epithelial cells in the urinary tract represents the most important determinant of pathogenicity. On the opposite side, the bladder epithelium shows a multifaceted array of host defenses including the urine flow and the secretion of antimicrobial substances, which represent useful tools to counteract bacterial infections. A vast amount of literature regarding the mechanism through which E.coli induces cystitis accounts for 95% of visits to physicians for symptoms of urinary tract infection. is defined as significant bacteriuria in the setting of symptoms of cystitis or pyelonephritis, It is pathogenic inflammation of the upper or lower urinary tract. Women are more commonly afflicted with UTIs and caused by common pathogens such as Escherichia coli (86%).