Vaccines aim to protect individuals from infectious diseases. The importance of vaccine such as prevention of hospital infections, cost efficiency, and overall protection to infections. The disadvantage of administration ...

Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-E coli) is the most underlying cause of food poisoning in worldwide. The influence of the food chain to these infections is debated. We aimed to identify the ...

Multiple Sclerosis (MS) is a neurodegenerative disease of the central nervous system, in which B-cells play an important role in its pathogenesis. However, Ocrelizumab (OCR) is a humanized anti-CD20 monoclonal antibody ...

Immunotherapy is revolutionizing the management of multiple solid tumors, and early data have revealed the clinical activity of PD-1/PD-L1 antagonists in small numbers of metastatic breast cancer patients. Clinical ...

Alzheimer disease (AD) is the most frequent cause of dementia in elderly. It leads to progressive cognitive decline due to accumulation of two proteins (β-amyloid peptide (Aβ) and Tau) in the forms of senile plaques and ...

Diabetic foot ulcer is a principal diabetic complication. It has been shown that diabetic patients have decreased growth factor concentrations in their tissues, particularly epidermal growth factor. Growth factor shortage ...

Myasthenia gravis (MG) is an autoimmune disease caused by complement-fixing antibodies against acetylcholine receptors (AChR). Cholinesterase inhibitors, Glucocorticoid , which is currently recommended as a first-line ...

Vitamin D is principally known for its role in calcium homeostasis, but preclinical studies implicate multiple pathways through which vitamin D may affect cardiovascular function and influence risk for heart failure. ...

Tay-Sachs disease is an autosomal recessive disease characterized by progressive neurologic degeneration, fatal in early childhood. In the Ashkenazi Jewish population the disease incidence is about 1 in every 3,500 ...

Immune checkpoint blockade has used as a treatment of patients with advanced melanoma and many other cancers. Blockade of inhibitory receptors, cytotoxic Tlymphocyte antigen 4 (CTLA-4) and programmed cell death receptor ...