dc.contributor.author | Ashmawy, Mohamed | |
dc.date.accessioned | 2019-04-20T10:27:52Z | |
dc.date.available | 2019-04-20T10:27:52Z | |
dc.date.issued | 2018-04-14 | |
dc.identifier.uri | http://repository.limu.edu.ly/handle/123456789/687 | |
dc.description | CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeat. This name
refers to the unique organization of short, partially palindromic repeated DNA sequences found in
the genomes of bacteria and other microorganisms. While seemingly innocuous, CRISPR
sequences are a crucial component of the immune systems of these simple life forms. The immune
system is responsible for protecting an organism’s health and well-being. Just like us, bacterial
cells can be invaded by viruses, which are small, infectious agents. If a viral infection threatens a
bacterial cell, the CRISPR immune system can thwart the attack by destroying the genome of the
invading virus. The genome of the virus includes genetic material that is necessary for the virus to
continue replicating | en_US |
dc.description.abstract | Genetic engineering, also called genetic modification, is the direct manipulation of an organism's
genes using biotechnology. It is a set of technologies used to change the genetic makeup of cells,
including the transfer of genes within and across species boundaries to produce improved or novel
organisms. New DNA is obtained by either isolating and copying the genetic material of interest
using recombinant DNA methods or by artificially synthesizing the DNA. A construct is usually
created and used to insert this DNA into the host organism.1 Now, a new revolution has seized the
scientific community. Within only a few years, research labs worldwide have adopted a new
technology that facilitates making specific changes in the DNA of humans, other animals, and
plants. This technology is referred to as “CRISPR,” and it has changed not only the way basic
research is conducted, but also the way we can now think about treating diseases.2 Now,
researchers use the same CRISPR strategy to take on threats like diseases. CRISPR can turn genes
on or off, or make them work in a different way, to protect your health | en_US |
dc.language.iso | en | en_US |
dc.publisher | faculty of Basic Medical Science - Libyan International Medical University | en_US |
dc.rights | Attribution 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
dc.title | Genome engineering using CRISPR | en_US |
dc.type | Other | en_US |